The distance between San Francisco to San Diego via Santa Cruz, San Luis Obispo, Santa Barbara, Anaheim is 889 Km by road. You can also find the distance from San Francisco to San Diego via Santa Cruz, San Luis Obispo, Santa Barbara, Anaheim using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from San Francisco to San Diego via Santa Cruz, San Luis Obispo, Santa Barbara, Anaheim for road driving directions!