The distance between Houston to Key west FL via New Orleans, Panama City Beach, Orlando, Port St. Lucie is 2300 Mi by road. You can also find the distance from Houston to Key west FL via New Orleans, Panama City Beach, Orlando, Port St. Lucie using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from Houston to Key west FL via New Orleans, Panama City Beach, Orlando, Port St. Lucie for road driving directions!