The driving time from Buffalo to Myrtle Beach via 26208 US-40 is 53 hours 53 minutes by road. You can also find other options to travel from Buffalo to Myrtle Beach via 26208 US-40 like bus, subway, tram, train and rail. To know the travel distances while planning a journey, find the
Distance from Buffalo to Myrtle Beach via 26208 US-40!