The distance between New Smyrna Beach to MAYO CLINIC JACKSONVILLE FLORIDA United States is 169 Mi by road. You can also find the distance from New Smyrna Beach to MAYO CLINIC JACKSONVILLE FLORIDA United States using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from New Smyrna Beach to MAYO CLINIC JACKSONVILLE FLORIDA United States for road driving directions!