The driving time from Roma Termini to Florence via Loreto, Assisi, Siena, Florence, Pisa is 9 hours 26 minutes by road. You can also find other options to travel from Roma Termini to Florence via Loreto, Assisi, Siena, Florence, Pisa like bus, subway, tram, train and rail. To know the travel distances while planning a journey, find the
Distance from Roma Termini to Florence via Loreto, Assisi, Siena, Florence, Pisa!