The driving time from Rome to Florence via Orvieto, Todi, Perugia, Gubbio, Cortona, Arezzo, Seina is 8 hours 40 minutes by road. You can also find other options to travel from Rome to Florence via Orvieto, Todi, Perugia, Gubbio, Cortona, Arezzo, Seina like bus, subway, tram, train and rail. To know the travel distances while planning a journey, find the
Distance from Rome to Florence via Orvieto, Todi, Perugia, Gubbio, Cortona, Arezzo, Seina!