The driving time from Florence to Rome via Assisi, Lanciano, San Giovanni Rotondo, Rome is 11 hours 4 minutes by road. You can also find other options to travel from Florence to Rome via Assisi, Lanciano, San Giovanni Rotondo, Rome like bus, subway, tram, train and rail. To know the travel distances while planning a journey, find the
Distance from Florence to Rome via Assisi, Lanciano, San Giovanni Rotondo, Rome!