The distance between Rome to Pisa via SR2, 53045 Montepulciano SI, 53100 Siena is 491 Km by road. You can also find the distance from Rome to Pisa via SR2, 53045 Montepulciano SI, 53100 Siena using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from Rome to Pisa via SR2, 53045 Montepulciano SI, 53100 Siena for road driving directions!