To find the driving direction from Rome to Florence via San Giovanni Rotondo, Lanciano, Macerata, Loreto, Assisi which is 1074 by road, click on Show Directions after entering start and end locations in the calculator control. It takes around 749 to reach Rome to Florence via San Giovanni Rotondo, Lanciano, Macerata, Loreto, Assisi. Tired of travelling by road? You can just fly from Rome to Florence via San Giovanni Rotondo, Lanciano, Macerata, Loreto, Assisi. Check the
Flight Time from Rome to Florence via San Giovanni Rotondo, Lanciano, Macerata, Loreto, Assisi before travelling.