The distance between Niagara-on-the-Lake to Manitoulin Island is 448 Km by road. You can also find the distance from Niagara-on-the-Lake to Manitoulin Island using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from Niagara-on-the-Lake to Manitoulin Island for road driving directions!