The distance between San Francisco to San Luis Obispo via Highway 1, Santa Cruz, Monterey is 3374 Mi by road. You can also find the distance from San Francisco to San Luis Obispo via Highway 1, Santa Cruz, Monterey using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from San Francisco to San Luis Obispo via Highway 1, Santa Cruz, Monterey for road driving directions!