The distance between Los Angeles to San Luis Obispo via pacific coast highway, Lompoc, Guadalupe is 381 Mi by road. You can also find the distance from Los Angeles to San Luis Obispo via pacific coast highway, Lompoc, Guadalupe using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from Los Angeles to San Luis Obispo via pacific coast highway, Lompoc, Guadalupe for road driving directions!