The driving time from Rome to Tuscany via Florence, Pisa, Venice, Vatican City is 15 hours 2 minutes by road. You can also find other options to travel from Rome to Tuscany via Florence, Pisa, Venice, Vatican City like bus, subway, tram, train and rail. To know the travel distances while planning a journey, find the
Distance from Rome to Tuscany via Florence, Pisa, Venice, Vatican City!