The distance between Sault Ste. Marie to Niagara Falls via Thru USA is 2216 Km by road. You can also find the distance from Sault Ste. Marie to Niagara Falls via Thru USA using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from Sault Ste. Marie to Niagara Falls via Thru USA for road driving directions!